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Medical Devices and Surgical Technology Week

Susan Hasty, Publisher

Table of Contents . . . July 25th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Devices and Surgical Technology Week | Other Publications

Diagnostics - High-throughput LC-MS-MS ketamine screen developed

Genomics & Genetics - Mixture modeling can improve quality of DNA microarray data

Imaging - 3D MDCT can replace conventional angiography of extremities

Leukemia Diagnostics -  Annexin A1 screen useful for hairy cell leukemia diagnosis

Thyroid Cancer - Galectin-3 immunoassay facilitates diagnosis of occult papillary thyroid carcinoma

Accreditation - Facility receives quality system certification to ISO 13485:1996

Acute Chest Pain - 64-Slice CT scanner introduced for cardiac, thoracic, and vascular imaging

Age-Related Blindness - Implantable chip may offer treatment for age-related blindness

Allergy Medicine - Grass pollen-specific marker allergens molecularly characterized

Alzheimer Disease - Scientists use FDDNP-PET to detect and quantify AD in living patients

Angina - Article concludes that TMR is safe, effective in most difficult cases

Angiology - Method devised for selective limitation of lumen diameter in corrosion casting

Arrhythmia - Implantable loop recorder is useful in detecting intermittent arrhythmias

Arterial Inflammation - FDA grants 510(k) clearance for high sensitivity CRP

Artificial Heart - Bronchial shunt flows characterized in AbioCor replacement heart recipients

Assisted Reproduction - Long-term ovarian function maintained in woman following autologous transplant

Atherosclerosis - 16-MDCT shows promise in detecting coronary artery atherosclerosis

Atrial Fibrillation - Device company meets with FDA regarding Revelation Tx

Bacterial Endotoxin - A synthetic peptide derived from BPI: aa 148-161 neutralizes endotoxin

Biotechnology - 3D optical photonic crystals with designed point defects generated

Biotechnology - Novel capillary-based microflow NMR probe developed

Blood Volume Analyzer - LA County hospital to obtain BVA-100 for CCU

Brain Metastases - Some aspects of managing brain metastases remain controversial

Brain Tumors - Diffusion tensor imaging of the brain is feasible

Brain Tumors - HMGA1 proteins are present in human astrocytomas and glioblastomas

Breast Cancer - Radiation and tamoxifen after breast-conserving surgery reduce tumor recurrence

Breast Cancer - Response submitted to FDA approvable letter for Combidex

Breast Cancer - Sales distribution agreement signed for the ComfortScan in India

Breast Cancer - Utility of sentinel lymph node biopsy in breast cancer reviewed

Breast Cancer - p300/CBP-associated factor is a p53 target in breast tumors

Bronchial Diseases - Virtual bronchoscopy can visualize the trachea and proximal bronchial tree

Burn Medicine - Novel allogeneic cultured dermal substitute system shows promise

Business Update - Biotech company appoints new president, CEO; company restructured

Business Update - Device maker expands Germany, Austria, United Kingdom operations

Business Update - Diagnostics company expands, relocates

Business Update - H-Quotient announces major software sale and listing change

Business Update - Marketing agreement announced for Vitagel and Cellpaker system

Business Update - Sale of Hill-Rom's Air-Shields infant-care business now complete

Business Update - Surgical supply firm adds 12 new contracts in June

Cancer Diagnosis - Space technology and dental techniques combine in new cancer detector

Cancer Therapy - The treatment of cancer pain should involve neurosurgical treatments

Cancer Therapy - Utility of radiofrequency ablation of liver metastases reviewed

Cancer Trends - Monoclonal antibody therapies continue rapid growth in cancer market

Cardia Safety Monitoring - $1.2M awarded to study technology for cardiac safety monitoring

Cardiovascular Disease - Parasympathetic cardiac nerve stimulation resolves atrial fibrillation

Cardiovascular Disease - Snoring induces massive pulmonary air embolism during pacemaker implantation

Chronic Heart Failure - Left ventricular is preferred over biventricular pacing in chronic heart failure

Chronic Lymphocytic Leukemia - CAMPATH B-CLL study fully enrolled; will evaluate prolonged survival

Chronic Tinnitus - Agreement signed to develop treatments for inner ear disorders

Cloning - U.S. Patent covers methods for producing cloned animals, embryos

Collaborations - Agreement signed to expand availability of high content screening

Collaborations - Alliance to create new products in hearing healthcare, communications industries

Collaborations - Companies to develop personalized dendritic-cell vaccines

Collaborations - Company to provide clinical trial support services

Collaborations - Generex announces joint venture and licensing arrangement for Oralin

Collaborations - Human in vitro diagnostics PCR patent license executed

Collaborations - IMS, informatics company, enter into comarketing agreement

Collaborations - MARtech under investigation for cell line development

Collaborations - Newton LIMS selected for quality control manufacturing facility in Spain

Collaborations - Strategic partnership signed for automated protein purification system

Colon Cancer - Colorectal cancer screening is more complete with colonoscopy than sigmoidoscopy

Cord Blood Banking - Fifth BioArchive order placed by cord blood bank company in Taiwan

Coronary Artery Bypass - Phase III CABG trial evaluating edifoligide proceeding as planned

Coronary Artery Bypass - Type A dissection linked to aortic connector device reported

Craniofacial Surgery - Improved pediatric cranioplasty technique developed

Cryopreservation - Chinese cord blood stem cell bank adopts BioArchive system

Cystic Fibrosis - New technique images gene expression in mice

Diagnostic Imaging - Values from thoracic CT scans of mesotheliomas lean towards congruence

Diagnostics - Breast Imaging System is granted Chinese patent

Diagnostics - Cardiac MRI safe in rats with implanted pacemakers

Diagnostics - Chromosomal deletions in frozen glioma samples aid sterotactic analysis

Diagnostics - ICD electrograms useful for estimating pre-arrythmic repolarization alternans

Diagnostics - KetoCare Ketone Test Strips launched for diabetics, low-carb dieters

Diagnostics - Proteomics-based screen identifies disease-associated humoral antigens

Diagnostics - Proton radiography can monitor patients who undergo proton radiotherapy

Diagnostics - Vitrea 2, Version 3.5 advanced visualization software announced

Diagnostics - X-ray scatter correction algorithm devised for cone beam CT imaging

Dieting - Public health groups warn about risks associated with low-carb diets

Drug Abuse - Alpha test of ValiMed impaired clinician solution initiated

Drug Delivery - Lactide/glycolide monomers can improve PLGA gentamicin release

Drug Delivery - Liposomal encapsulation of nisin and lysozyme enhances anti-Listeria efficacy

Eating Disorders - Electrogastrography helps determine pathophysiology of eating disorders

Environmental Health - Bioassays for measurement of herbicide toxicity evaluated

Facial Wrinkles - FDA clears ThermaCool device for treatment of facial wrinkles and rhytids

Fibromyalgia - Hyperbaric oxygen therapy relieves pain of syndrome

Finance - Blood analysis systems maker to be added to Russell 2000 Index

Finance - Board of directors of disposables company approves stock repurchase

Finance - Cardiac device maker reports 24th consecutive quarter of sales growth

Finance - Cardiology company demands delisting from German stock exchange

Finance - Device company completes public offering of $600M

Finance - Device firm closes oversubscribed $27.5M round of private financing

Finance - Device firm signs definitive agreements to sell $13.1M of common stock

Finance - Diagnostics company announces $13.5M financing

Finance - Diagnostics maker reports new option grants

Finance - Exchange offer for shares of Drew Scientific Group extended

Finance - Gastric retention system maker to be added to Russell 2000 and 3000 indexes

Finance - Lab data company reports record fourth quarter

Finance - Medical device company secures $11M in Series B financing

Finance - Spine-focused company underwriters exercise over-allotment option

Food-Borne Disease - Covalent mix ELISA suitable for swine Salmonella screening

Gallbladder Surgery - Research emphasizes value of minimally invasive surgery for complex procedures

Gastric Bypass Surgery - UNM Hospital suspends gastric bypass surgery

Gastric Cancer - Microarray analysis reveals NOL8 overexpression in diffuse gastric cancer

Genomics - Microarray detection of transcription factor-binding motifs enhanced

Genomics - Novel approach improves automation of antibody microarray analysis

Genomics & Genetics - Gene guns useful for cellular delivery of lipophilic dyes

Glomus Tumors - Glomus tumors of the head and neck are usually diagnosed using CT and MRI.

Glucose Monitoring - New device will allow measuring blood sugar with a wave of the arm

Gout - Cardiome receives FDA approvable letter on oxypurinol for gout

Gynecologic Surgery - Surgical procedure prevents genital prolapse following Burch colposuspension

Gynecology - Supracervical hysterectomy is associated with urinary symptoms

HIV Diagnosis - FDA approves OraQuick HIV-1/2 test to detect HIV-2 in oral fluid

HIV/AIDS - P24 tag useful tool for purifying and detecting recombinantly expressed scFvs

HIV/AIDS Research - TARTAR dimer therapeutic target for treatment of HIV-1 infection

HIV/AIDS-Related Conditions - Inflammatory and reactive arthropathies more prevalent in HIV infection

HIV/AIDS-Related Disease - QTD PCR of oral-wash samples accurate and noninvasive for diagnosis of PCP

Healthcare Coverage - Insurance coverage for EVLT procedure reaches 80 million Americans

Heart Attack - AEDs sold for delivery to customers in Japan

Heart Attack - FDA grants clearance for two additional claims for BNP test

Heart Attack - FDA grants clearance to market pediatric defibrillation pads

Heart Disease - Cardiac monitoring essential in patients with blood disorder

Heart Transplantation - Cardiac xenotransplantation may be feasible in the future

Hemodialysis - Diagnostic model helps detect cardiomegaly in dialysis patients

Hemotoxicity - HemoGenix launches HALO hemotoxicity test platform in Korea

Hip & Knee Replacements - Tucson Orthopaedic Institute to provide surgeon training in MIS procedures

Hyperhidrosis - Excessive sweating is a medical condition that can be treated

Imaging - Halifax Medical Center selects VERICIS from Camtronics

Imaging - LCD systems installed at Fairview Health Services

Imaging - New noninvasive method developed for lung diagnostics

Immunoassays - AxSYM diagnostic testing menus expanded in U.S.

Immunology - Cryo-electron tomography used to characterize individual IgG molecules

Immunology - DC maturation by AdV transduction enhances tumor Ag-specific T cell response

Immunology - Dendritic cell expression of Ig-like transcripts characterized

Immunology - Potential uses of RapidMist technology in transmucosal vaccines discussed

Immunology - PrP-GFP expression models analyze activity of Prnp gene during prion infections

Immunology - Valpha24 NK T cells of CD4+ subset develop in the early fetal thymus

Infectious Disease - Brugia Rapid test detects filaria-specific IgG4 antibodies in endemic areas

Information Technology - Company launches unified platform for eCDM: RAVE 5.0

Information Technology - Laboratory-Collection Manager launched to enhance specimen-collection accuracy

Information Technology - Picis selected to automate operating rooms in seven facilities

Information Technology - Surgical device company begins design of commerce website

Interventional Cardiology - European scientific panel recommends approval of Angiox

Ion Therapy - Most powerful laser to date could revolutionize cancer treatment

Joint Replacement - Wear patterns of UHMWPE hip liners characterized

Keratoconjunctivitis Sicca - Microvascular submandibular gland autotransfer effective

Kidney Cancer - Radiofrequency ablation spares kidney, kills tumor

Legal Issues - Inamed Corp. reaches settlement of patent litigation over gastric banding

Legal Issues - Laser company, Palomar agree to settlement of patent litigation

Leukemia - Differentially expressed molecules in adult T-cell leukemia cells identified

Lipid Studies - LDL apheresis can attenuate acute anterior ischemic optic neuropathy

Liver Regeneration - Beta-2-GPI is growth regulated and plays role as survival factor for hepatocytes

Lung Cancer - FISH analysis of p53 and chromosome 17 has limited prognostic value

Lymphoma - Recurrent syncope can mark Burkitt lymphoma at carotid bifurcation

Mammography - FDA approves marketing of flat-panel DomeC5i system for mammograms

Market Analysis - Biocompatibility to widen the scope of biomaterial applications

Market Analysis - Greater usage of disc technology for back pain predicted

Medical Devices - Polyimide hollow-fiber oxygenator developed

Medical Kits - Hatteras Yachts makes "First Responder" medical kit standard onboard equipment

Medicare - Age, race, socioeconomics affect billing claims for mammography

Medication Safety - Ann Arbor hospital selects pharmacy IV automation technology

Mergers & Acquisitions - Agreement signed for acquisition of Concorde Microsystems

Mergers & Acquisitions - Air-Shields acquisition extends company's portfolio into neonatal market

Mergers & Acquisitions - Closing date of offer on Aventis postponed

Mergers & Acquisitions - Company amends letter of intent to acquire interest in sixth dialysis center

Mergers & Acquisitions - Device company completes acquisition of Interpore International

Mergers & Acquisitions - Division of Matria Healthcare to be acquired

Mergers & Acquisitions - Firm enters orthopedic, spinal surgery arena through acquisition of NeuColl

Mergers & Acquisitions - Henry Schein completes acquisition

Mergers & Acquisitions - Interpore Cross International stockholders approve acquisition

Mergers & Acquisitions - KS E-Media Holdings acquires Chinese biomedical company

Mergers & Acquisitions - Merger agreement with Chromos announced

Microarray Technology - CustomArray product line expanded with introduction of CustomArray12K

Molecular Toxicology - Toxicology grant awarded from NIH

Multiple Myeloma - Methylation epigenetically regulates tumor-suppressing genes

Myocardial Function - Strain and strain rate are new echo parameters of regional myocardial function

Nanoscience - NanoArrayer trial planned at Oak Ridge National Laboratory

Neurology - Ethanol superior to formalin for mRNA preservation in tissue

Neuroscience - Brain emboli dissemination after captive bolt stunning can spread BSE in animal

Neuroscience - Delayed genomic responses to murine brain ischemia characterized

Neuroscience - PSD-95 protein involved in psychostimulant-induced plasticity

Neuroscience - Utility of auditory brainstem implants reviewed

Neuroscience - Utility of upper extremity neuroprosthetics reviewed

Obesity - Implantable gastric stimulation does not alter gastrointestinal anatomy

Obesity Surgery - Controversies in laparoscopic adjustable gastric banding outlined

Obstetrics - ELF magnetic fields cause no adverse effects in pregnant mice or offspring

Obstetrics - MRI more accurate for detecting prenatal cleft lip and palate than sonography

Obstetrics - PCR detects primary CMV infection in seronegative pregnant women

Obstetrics - Prosthetic valve thrombosis remains a deadly complication

Obstetrics - Vacuum-assisted deliveries are safe alternative to forceps

Obstructive Sleep Apnea - Device found valuable in detecting OSA during overnight home oximetry

Ocular Cancer - Ultrasonic 2-D spectrum analysis useful for ocular tumor characterization

Oral Surgery - Endosseous implant-induced rhino-sinusitis reported

Oral Surgery - Onlay bone grafts with implants effective for severely resorbed maxillae

Orthopedic Surgery - Suture anchor failure in anterior shoulder instability repair reported

Osteoporosis - Are you less likely to be truthful about your weight, age, or height?

Ovarian Cancer - Ovarian cancer test to advance through collaboration

Overactive Bladder - Health Canada approves OXYTROL for the treatment of overactive bladder

Pain Medicine - Routine MRI recommended for patients with facial pain

Pain Therapy - Nitric Oxide-enhancing COX-2 inhibitor advanced to phase II testing

Papillary Thyroid Cancer - JNK activation may play role in pathogenesis

Patents - European patent granted for technology to treat gene abnormalities

Patents - Two patents awarded for applications of electroporation therapy

Pericardial Disease - Acute and chronic-constrictive pericardial heart disease is treated surgically

Personalized Medicine - Data mining, predictive modeling provided for personalized medicine models

Personnel - David Walshaw appointed as head of production planning at biocatalysis company

Personnel - Device maker appoints Paul A. Sobotka chief medical officer

Personnel - Medical device manufacturer appoints new president and chief executive officer

Personnel - Medical device manufacturer names new chief executive officer

Personnel - Medical product manufacturer announces COO of surgical innovations division

Personnel - Neil Luckianow to head national sales team for cholesterol-monitor company

Personnel - Ophthalmology company names Michael J. Regan to the board of directors

Personnel - Stephen Chang joins board of directors at cell line production company

Personnel - Terrence A. Noonan named to fill role of lead director at device firm

Prostate Cancer - MMP-13 is androgen-regulated in prostate cancer

Prostate Cancer - New advances in prostate cancer molecular imaging reported at meeting

Prostate Cancer - Postoperative urinary and sexual function are concerns after prostatectomy

Prosthetics - Engineering breakthrough develops artificial neuron that "learns"

Protein Discovery - First sale of SpectRIM announced

Protein Research - Agilent Lys Tag 4H reagent kit introduced for protein identification

Proteomics - CIEF-RPLC-MS protein analysis system developed

Proteomics - Double chip protein array using recombinant scFv fragments developed

Proteomics - Narrow Bore Triple Resonance MAS probes introduced

Proteomics - Novel subcellular extraction procedure facilitates protein analysis

Proteomics - SELDI technology aids analysis in kidney-transplantation rejection study

Pulmonary Medicine - Flow-type spirometer errors that elevate test results described

Radiation Oncology - Elekta chosen to increase effectiveness of oncology treatment solutions

Radiology - Patients with inoperable tumors benefit from radiofrequency ablation

Renal Cell Carcinoma - Renal epithelial neoplasms can be associated with familial tumor syndromes

Renal Disease - Utility of testosterone replacement therapy in ESRD patients reviewed

Respiratory Medicine - Novotizer dry powder inhaler superior to Turbuhater

Retrovirology - Luciferase-based assay rapid and sensitive for detection of retrovirus entry

Sinusitis - Inflammatory diseases of the nasal sinuses can have serious complications

Sjogren Syndrome - GRAP gene may be involved in Sjogren syndrome pathogenesis

Skin Grafts - FDA approves leeches as medical devices

Soft Tissue Allografts - BioCleanse process offers sterilized soft tissue allografts

Stem Cell Reseach - ABCG2 positive limbal epithelial cells putative corneal epithelial stem cells

Stem Cell Research - Mitochondrial and death receptor pathways in neural SC differentially regulated

Stem Cell Research - Poly(2-hydroxyethyl methacrylate)-based slabs used for embryonic SC support

Stem Cell Research - Self-renewing divisions of hematopoietic SC increased in absence of P18(INK4C)

Stem-Cell Research - A small modulatory dsRNA specifies fate of adult neural stem cells

Stem-Cell Research - Adenylyl cyclase seen to restrict clonal propagation of pluripotent stem cells

Stem-Cell Research - Glioma tropic neural stem cells consist of astrocytic precursors

Stem-Cell Research - HB-GAM inhibits proliferation and enhances differentiation of neural stem cells

Stem-Cell Research - Novel mechanism for regulating clonal propagation of ES cells is described

Stem-Cell Research - Novel model allows analysis of molecular pathogenesis of neuronal degeneration

Stem-Cell Research - Scaffold hybridized with marrow stromal stem cells provides good osteoconduction

Stem-Cell Research - Sox-2 regulatory regions display activity in two types of multipotent stem cells

Stem-Cell Transplantation - EBMT Risk Score for CML patients receiving stem cell transplants is validated

Stem-Cell Transplantation - Heart allografts from donors lacking Flt3 ligand exhibit prolonged survival time

Stem-Cell Transplantation - RAG-1 is a suitable mouse model for mitochondrial DNA disease

Stress - Workplace stress reliever produced launched

Surgical Mesh - Two new hernia repair devices introduced

Thyroid Cancer - Genetic markers for malignant thyroid tumors identified

Thyroid Disease - Sutureless technique is effective for delicate thyroidectomy

Tibial Fixation - Bio-Intrafix launched for ACL repair

Tissue Engineering - Fluoride substitutions of HAP viable for tissue replacement using stem cells

Tonsillitis - Coblation tonsillectomy offers more benefits than electrocautery, study shows

Tuberculosis - VScan maker requested to participate in major test

Urinary Incontinence - Mini-incisional Burch urethropexy is efficacious in treatment of GSI

Vascular Disease - Scientists in Japan find PET assesses infection in vessel graft

Wilms Tumor - SIOP trials and studies evaluate the prognosis of Wilms tumor patients

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