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Leukemia Diagnostics
Annexin A1 screen useful for hairy cell leukemia diagnosis
July 25th, 2004
An immunocytochemical annexin A1 screen facilitates hairy cell leukemia diagnosis. "A marker capable of distinguishing with certainty between hairy cell leukemia and other B-cell malignant disease would be of great diagnostic value," hematologists in Italy explained. "Through gene expression profiling, annexin A1 (ANXA1) has been identified as a gene that is upregulated in hairy cell leukemia." B. Falini and colleagues at the University of Perugia performed "immunostaining of 500 B-cell tumors with a specific anti-ANXA1 monoclonal antibody and showed that ANXA1 protein expression is specific to hairy cell...
Source: Medical Devices & Surgical Technology Week (2004-07-25)
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