Anti-Infectives
Alkaline cleaner can inactive scrapie agent on medical devices
Published in Medical Devices and Surgical Technology Week, August 1st, 2004
In a recent study from Germany, the "capacity of a routinely available alkaline cleaner for medical devices to inactivate the causative agent of a transmissible spongiform encephalopathy (TSE) was tested."
"The co-incubation of brain homogenates, prepared from terminally ill scrapie-infected hamsters, with the cleaner led to the denaturation of misfolded protein as the proteinase K-resistant prion protein was no longer detectable after such treatment," reported M. Baier and colleagues working at the Robert Koch Institute in Berlin. "In addition, intracerebral...
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