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Oncology

Proteo-genomics system identifies malignant antibody targets

Published in Medical Devices and Surgical Technology Week, August 1st, 2004

A proteo-genomics system can help identify antibody targets in cancer.

According to researchers in Massachusetts, "[i]dentification of antibody targets associated with malignant disease is indispensable to developing passive and active antibody-based therapeutics or diagnostic agents."

To facilitate this process, Y.Y. Huang and colleagues at Framingham-based Genzyme Corporation "developed a novel technique combining Western blotting, genetic profiling, and mass spectroscopy that allows for the rapid and unambiguous identification of such antigens in a high-throughput manner."

"Herein, we demonstrate this technique, designated Ab...

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