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DNA Research

Viral DNA damage in presence of RB, UV light may make normal repair less likely

Published in Medical Devices and Surgical Technology Week, November 7th, 2004

Viral DNA damage in presence of riboflavin and UV light may make normal repair less likely.

Researchers in the United States are "developing a technology based on the combined application of riboflavin (RB) and light for inactivating pathogens in blood products while retaining the biological functions of the treated cells and proteins.

"Virus and bacteria reduction measured by tissue culture infectivity or colony formation with UV light alone and in combination with RB yield equivalent results. The effects of RB as a sensitizing agent on DNA in white cells, bacteria and viruses in combination with UV light exposure have been evaluated."

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