Published in Medical Devices and Surgical Technology Week, February 6th, 2005
"Aristolochic acid (AA), the active compound found in Aristolochia extracts, has been used as a traditional medicine," scientists in the United States explained. "However, products containing AA were withdrawn from the market in the early 1980s because AA was found to be a potent carcinogen."
"Some genotoxicity studies of AA were conducted after the carcinogenicity of AA was reported," noted H. Zhang and colleagues at Covance Laboratories Inc., who conducted a study "to check the ability of simplified, screening tests for genotoxicity to...
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