Virology
In situ hybridization rapidly identifies EBV infection in single cells
Published in Medical Devices and Surgical Technology Week, February 13th, 2005
EBV virus "is associated with malignancies such as lymphoma and carcinoma," pathologists in Canada explained. "Infection of cells with EBV may result in either lytic infection with production of viral particles, characterized by the presence of linear DNA forms, or latent infection, characterized by either episomal or integrated DNA forms."
"To examine whether the different lytic and latent EBV DNA forms can reliably be distinguished in single human cells, in situ hybridization was performed in EBV-positive cell lines," in a study conducted...
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