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Bacteriology

Novel microarray enables direct detection of S. aureus mRNA

Published in Medical Devices and Surgical Technology Week, March 20th, 2005

A novel microarray system enables the direct detection of bacterial mRNA.

"The direct detection of mRNAs from bacterial cultures on a DNA array without amplification and labelling would greatly extend the range of applications suitable for microarray analysis," microbiologists in the Netherlands explained.

In their study, R.M. Anthony and coauthors working at KIT Biomedical Research in Amsterdam achieved the "direct detection of 23S rRNA and seven mRNA species from total Staphylococcus aureus RNA prepared using commercially available RNA purification columns followed by fluorescent detection on a flow through microarray."

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