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Prostate Cancer

uPA mRNA and uPAR mRNA expression seen in adenocarcinomas & benign hyperplasias

Published in Medical Devices and Surgical Technology Week, April 17th, 2005

Urokinase-type plasminogen activator mRNA and uPA receptor mRNA expression are found in adenocarcinomas and benign hyperplasias

According to recently published research in the International Journal of Cancer, "The plasminogen activation (PA) cascade participates in degradation of extracellular matrix during cancer invasion.

"We have studied the expression of urokinase-type plasminogen activator (uPA) mRNA, uPA receptor (uPAR) mRNA and immunoreactivity, and type-1 plasminogen activator inhibitor (PAI-1) mRNA and immunoreactivity in 16 prostate adenocarcinomas and 9 benign prostate hyperplasias."

"uPA mRNA and uPA,R mRNA...

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