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Breast Cancer

Methyl mercury influences growth-related signaling in breast cancer cells

Published in Medical Devices and Surgical Technology Week, May 8th, 2005

Methyl mercury influences growth-related signaling in breast cancer cells.

According to a study from Australia, "Environmental contaminants have been shown to alter growth-regulating signaling pathways through molecular mechanisms that are mainly unclear.

"Here we report that within a narrow concentration range (0.5-1 mcM) methyl mercury (MeHg) significantly stimulated growth of MCF-7 cells, induced Ca2+ mobilization, and activated extracellular signal-regulated kinase 1/2 (Erk1/2)."

"MeHg modulated E-2-dependent stimulation of growth in a dose-dependent manner, although MeHg neither suppresses nor increases constitutive E-2...

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