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Cardiology

When medium-chain fatty acid is available, glucose oxidation remains suppressed

Published in Medical Devices and Surgical Technology Week, May 29th, 2005

Researchers have investigated the influence of calcium-induced workload transitions and fatty acid supply on myocardial substrate selection.

According to recent research from Finland, "Because of differences in energy yield and oxygen demand, the selection of oxidative fuels is important in the hypoxic or ischemic heart muscle. The aim of [our] study was to clarify the contradictions observed in the effects of workload and fatty acid supply on myocardial fuel preference in isolated perfused rat hearts."

A. Alarami and colleagues of the University of Oulu explained, "Nuclear magnetic resonance spectroscopy combined with the administration of...

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