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Bioinformatics

Web tools facilitate the design and optimization of RNAi constructs

Published in Medical Devices and Surgical Technology Week, September 4th, 2005

Web tools facilitate the design and optimization of RNAi constructs.

According to a study from Germany, "RNA interference (RNAi) has become a powerful genetic approach to systematically dissect gene function on a genome-wide scale. Owing to the penetrance and efficiency of RNAi in invertebrates, model organisms such as Drosophila melanogaster and Caenorhabditis elegans have contributed significantly to the identification of novel components of diverse biological pathways, ranging from early development to fat storage and aging."

"For the correct assessment of phenotypes, a key issue remains the stringent quality control of long...

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