Published in Medical Devices and Surgical Technology Week, January 1st, 2006
"The development of accurate and sensitive methodologies to detect small chromosomal imbalances (<3 Mb) is extremely important in clinical diagnostics and research in human genetics," scientists in Cyprus noted. "The technique of array-comparative genomic hybridization (CGH) using BAC and PAC clones is very sensitive methodology and is rapidly becoming the method of choice for high-resolution screening of genomic copy-number changes."
"An alternative methodology to CGH is the multiplex amplifiable probe hybridization (MAPH) methodology, a...
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