Genetics & Genomics
Microarray-based system devised for multiplex amplifiable probe hybridization
Published in Medical Devices and Surgical Technology Week, January 1st, 2006
"The development of accurate and sensitive methodologies to detect small chromosomal imbalances (<3 Mb) is extremely important in clinical diagnostics and research in human genetics," scientists in Cyprus noted. "The technique of array-comparative genomic hybridization (CGH) using BAC and PAC clones is very sensitive methodology and is rapidly becoming the method of choice for high-resolution screening of genomic copy-number changes."
"An alternative methodology to CGH is the multiplex amplifiable probe hybridization (MAPH) methodology, a...
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