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Neuroscience

Murine striatal glutamate levels differ in high and low responders to novelty

Published in Medical Devices and Surgical Technology Week, January 1st, 2006

Striatal glutamate levels vary in mice with different responses to novelty.

In a recent study, neuroscientists in the United States sought to "determine whether there was a difference in glutamate within the dorsolateral striatum in mice exhibiting either a high (HR) or low (LR) locomotor response to a novel environment."

"The number of line crossings over a 30-min-period when the mice were placed in a novel environment was determined, and those mice for which the values were above the mean were in the HR group and those with the values below the mean were in the LR group," explained S.S. Shakil and coauthors at the VA Medical Center in...

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