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Angiology
Lectin-like oxidized LDL receptor-1 is expressed after vascular injury
April 11th, 2006
According to a study from Japan, lectin-like oxidized LDL receptor-1 (LOX-1) is expressed in smooth muscle cells (SMC) after vascular injury. "LOX-1 is an oxidized LDL receptor, and its role in restenosis after angioplasty remains unknown. We used a balloon-injury model of rabbit aorta, and reverse transcription-polymerase chain reaction revealed that LOX-1 mRNA expression was modest in the non-injured aorta, reached a peak level 2 days after injury, and remained elevated until 24 weeks after injury," wrote H. Eto and colleagues, Kagoshima University. "Immunohistochemistry and in situ hybridization showed that LOX-1 was not detected in the media of...
Source: Medical Devices & Surgical Technology Week (2006-04-11)
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