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Angiology
Plasma N-terminal pro-atrial natriuretic peptide is key correlate of vascular endothelial function
April 11th, 2006
In a large community-based sample, a conservative strategy relating several biomarkers to vascular endothelial function identified plasma N-terminal pro-atrial natriuretic peptide as a key correlate of mean flow under basal conditions and of flow-mediated dilation in response to forearm cuff occlusion. Investigators publishing in the journal Circulation report, "Endothelial dysfunction is a critical intermediate phenotype in the pathogenesis of cardiovascular disease. We evaluated the relative contributions of distinct biological pathways to interindividual variation in endothelial function by relating prototype biomarkers (representing these pathways) to...
Source: Medical Devices & Surgical Technology Week (2006-04-11)
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