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Breast Cancer
Breast cancer patients with ATM gene alteration may develop fibrosis after radiotherapy
April 11th, 2006
A recent study suggests an association between ATM and the development of Grade 3 fibrosis in breast cancer patients treated with radiotherapy. Scientists in the United States conducted a study "to examine the hypothesis that women who are carriers of genetic alterations in the ATM gene are more likely to develop subcutaneous fibrosis after radiotherapy for treatment of breast cancer compared with patients who do not possess DNA sequence variations in this gene." "DNA samples isolated from fibroblast cell lines established from 41 women treated with postmastectomy radiotherapy for breast cancer were screened for genetic variants in...
Source: Medical Devices & Surgical Technology Week (2006-04-11)
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