Hematology
In pediatric cardiac surgery, blood transfusions may be reduced with use of aprotinin
Published in Medical Devices and Surgical Technology Week, April 18th, 2006
According to a recent report from the United States, "Aprotinin, a potent antifibrinolytic drug, reduces the proportion of adults who receive blood transfusions during cardiac surgery, although the effect in children remains unclear. We performed a systematic review of the literature to identify all English-language, randomized controlled trials of aprotinin involving children undergoing corrective or palliative cardiac surgery with cardiopulmonary bypass."
"All studies were assessed for methodological quality, and sources...
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