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Orthopedics

Total hip replacement metal-on-metal prostheses can cause hypersensitivity

Published in Medical Devices and Surgical Technology Week, August 13th, 2006

A hypersensitivity-like reaction with aseptic inflammatory changes is demonstrated with second-generation metal-on-metal total hip replacements after 7 years.

"Second-generation metal-on-metal total hip replacements were introduced in the early 1990s with the aim of eliminating polyethylene wear and the resulting complications of osteolysis and aseptic loosening. The goal of the present study was to evaluate the intermediate-term results in a series of patients who were managed with one of these implants. Between 1994 and 2002, we performed 640 total hip replacements in 591 patients with use of a Bicon-Plus cementless threaded cup with a polyethylene liner housing a...

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