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Drug Delivery

Mitomycin C incorporated into P(HEMA) hydrogels inhibits cell proliferation

Published in Medical Devices and Surgical Technology Week, October 8th, 2006

A slow release form of mitomycin C (MMC) incorporated into P(HEMA) hydrogels inhibits cell proliferation in vitro.

According to a study from the United States, "The technique of MMC drug delivery and its application in glaucoma surgery are not standardized with resultant inconsistencies in the results. Also, one time application of MMC does not seem to have the same efficacy after glaucoma drainage device surgeries compared with trabeculectomies. This preliminary study examined the efficacy of a slow release form of MMC for its ability to inhibit cell proliferation in vitro."

D.A. Blake and colleagues, Tulane University, wrote, "MMC was incorporated...

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