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Cardiology

Morphine improves recovery of ventricular function after cardiopulmonary bypass

Published in Medical Devices and Surgical Technology Week, October 15th, 2006

In patients undergoing cardiopulmonary bypass (CPB), global ventricular function is enhanced by the administration of morphine prior to cardioplegic arrest.

According to a study from the United States, "Experimental studies have shown that opioids protect the myocardium from ischemic injury and that opioid cardioprotection is enhanced by the coadministration of volatile anesthetics. Previous data suggest that morphine produces a more potent cardioprotective effect than fentanyl. The present study investigated the effect of the choice of intraoperative opioid (morphine or fentanyl) on recovery of myocardial function after coronary artery bypass graft (CABG)...

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