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Microarrays

New findings from Center for Biologics Evaluation and Research in the area of microarrays described

Published in Medical Devices and Surgical Technology Week, July 1st, 2007

Research findings, "Microarray assay for evaluation of the genetic stability of modified vaccinia virus Ankara B5R gene," are discussed in a new report. "Adverse events associated with the use of live smallpox vaccines have led to the development of a new generation of attenuated smallpox vaccines that are prepared in cultured cells as alternatives. The inability to conduct direct clinical evaluation of their efficacy in humans demands that licensure be based on animal studies and exhaustive evaluation of their in vitro properties," investigators in the United States report.

"One of the most important characteristics of live viral vaccines is their genetic stability,...

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