Lung Cancer

Recent findings from University of Texas highlight research in lung cancer

Published in Medical Devices and Surgical Technology Week, February 3rd, 2008

According to recent research from the United States, "Background Lung cancers develop via multiple genetic and epigenetic changes, including inactivation of tumor suppressor genes. We previously cloned human G protein-coupled receptor family C type 5A (GPRC5A), whose expression is suppressed in some human lung carcinoma cells, and its mouse homolog Gprc5a."

"Methods We generated Gprc5a knockout mice by homologous recombination and studied their phenotype by macroscopic observation and microscopic histologic analysis of embryos and lungs of 1- to 2-year-old mice. GPRC5A mRNA expression was analyzed by reverse transcription-polymerase chain reaction in surgical specimens...

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Source: Medical Devices and Surgical Technology Week (2008-02-03)

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