Acute Lymphoblastic Leukemia

New acute lymphoblastic leukemia study findings recently were reported by G. Cario and co-researchers

Published in Medical Devices and Surgical Technology Week, February 3rd, 2008

According to a study from Hannover, Germany, "Purpose Applying current diagnostic methods, overt CNS involvement is a rare event in childhood acute lymphoblastic leukemia (ALL). In contrast, CNS-directed therapy is essential for all patients with ALL because without it, the majority of patients eventually will experience relapse."

"To approach this discrepancy and to explore potential distinct biologic properties of leukemic cells that migrate into the CNS, we compared gene expression profiles of childhood ALL patients with initial CNS involvement with the profiles of CNS-negative patients. Patients and Methods We evaluated leukemic gene expression profiles from the...

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Source: Medical Devices and Surgical Technology Week (2008-02-03)

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