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Mass Spectrometry

Findings from M. Yamada and co-researchers advance knowledge in mass spectrometry

Published in Medical Devices and Surgical Technology Week, March 9th, 2008

According to recent research from Utsunomiya, Japan, "Nandrolone ( 17 P-hydroxy-4-estren-3 -one, NAD) is an endogenous steroid hormone; thus, the detection of its metabolites is not conclusive of NAD doping in racehorses. NAD doping control in male horses is based on the threshold, namely, the concentration ratio of 5 alpha-estran-3 beta,17 alpha-diol (ETA) to 5(10)-estren-3 beta,17 alpha-diol (ETE)."

"The ETA/ETE ratio of 1/1 was determined based on statistical data of authentic horses in International Federation of Horseracing Authorities. To individuals with complex metabolic disorders, however, such a threshold might not be applicable. The aim of this study was to...

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