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Osaka University reports research in life sciences

Published in Medical Devices and Surgical Technology Week, June 1st, 2008

Data detailed in 'Basic fibroblast growth factor regulates expression of heparan sulfate in human periodontal ligament cells' have been presented. "Heparan sulfate (HS) proteoglycan is a widely distributed biological molecule that mediates a variety of physiological responses in development, cell growth, cell migration, and wound healing. We examined the effects of basic fibroblast growth factor-2 (FGF-2), which is known to modulate extracellular matrix (ECM) production of various cell types, on the production of HS proteoglycan by human periodontal ligament (HPDL) cells," scientists in Suita, Japan report.

"We also examined the effects of FGF-2 on the expression of...

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