BioMed Central

Mouse ovaries and testes age in unique ways

Published in Medical Devices and Surgical Technology Week, June 22nd, 2008

Aging leads to large changes in gene activity in the ovaries of mice, but only limited changes in testes, according to research published in the open-access journal, BMC Biology. A lifespan-extending calorie-restricted diet reversed some of the aging effects – but, unlike the widespread changes observed in somatic organs, it had an impact only in a small number of gonad-specific genes.

As well as tackling one of the key questions of ageing – by exploring if reproductive organs age in the same way as other body organs – this research is important in the light of the trend for some women in developed countries to put off childbearing until later in life.

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Source: Medical Devices and Surgical Technology Week (2008-06-22)

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