Tufts University

Tufts researchers discover link between DNA palindromes and disease

Published in Medical Devices and Surgical Technology Week, August 3rd, 2008

In the past 10 years, researchers in genome stability have observed that many kinds of cancers are associated with areas where human chromosomes break. More recently, scientists have discovered that slow or altered replication causes chromosomal breaking. But why does DNA replication stall'

In a Tufts University study published in the July 14 issue of "Proceedings of the National Academy of Sciences of the United States of America," a team of biologists have found a relationship between peculiar DNA sequences named palindromes and replication delays.

Sergei Mirkin, White Family Professor of Biology at Tufts' School of Arts and Sciences, along with...

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Source: Medical Devices and Surgical Technology Week (2008-08-03)

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