Surgery

Investigators at AstraZeneca release new data on surgery

Published in Medical Devices and Surgical Technology Week, August 3rd, 2008

According to a study from Lund, Sweden, "Budesonide, unlike fluticasone propionate, undergoes fatty acid esterification in the lungs, and there is a need to characterize fully the distribution and fate of the two drugs after inhalation in humans. This open-label, randomized study was performed in adults undergoing whole lung or lobar resection resulting from lung cancer."

"Patients were given single 1000-mu g doses of both budesonide and fluticasone propionate via dry powder inhalers before surgery. Tissue samples from peripheral and central lung, an ex vivo bronchial brush sample and intercostal muscle, together with plasma samples, were taken during surgery and...

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Source: Medical Devices and Surgical Technology Week (2008-08-03)

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