Epilepsy

Research from Woodville SA has provided new data on epilepsy

Published in Medical Devices and Surgical Technology Week, November 23rd, 2008

"Lamotrigine (LTG) is used currently as monotherapy or, more frequently, as add-on therapy with other antiepileptic drugs. It demonstrates efficacy against partial seizures, primary and secondary tonic clonic seizures, absence seizures, and drop attacks," scientists writing in the journal Therapeutic Drug Monitoring report.

"LTG pharmacokinetics is complicated by coadministration with other antiepileptic drugs Such as valproic acid phenytoin, or carbamazepine. The wide interpatient variability in LTG dosage required to attain therapeutic plasma LTG concentrations for seizure control Suggests that LTG is a good candidate for therapeutic drug monitoring (TDM). In...

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Source: Medical Devices and Surgical Technology Week (2008-11-23)

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