Life Sciences

Scientists at Pharmacopeia detail research in life sciences

Published in Medical Devices and Surgical Technology Week, January 4th, 2009

"A simple, sensitive gradient RP-LC assay method has been developed for the quantitative determination of vardenafil HCl in bulk drug and in pharmaceutical dosage forms, used to treat erectile dysfunction. The developed method is also applicable for the related substances determination," scientists in Hyderabad, India report.

"Efficient chromatographic separation was achieved on a C18 stationary phase with simple mobile phase combination delivered in a gradient mode and quantification was carried out using ultraviolet detection at a flow rate of 1.0 mL min(-1). In the developed LC method the resolution between vardenafil and its four potential impurities was found to be...

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Source: Medical Devices and Surgical Technology Week (2009-01-04)

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