Xenotransplantion

Researchers from University of Sydney report on findings in xenotransplantion

Published in Medical Devices and Surgical Technology Week, January 11th, 2009

"Xenotransplantation could ameliorate the severe shortage of donor organs. The initial results of transplantation from genetically-modified pig donors to primate recipients suggest that hyperacute rejection can be overcome, but thrombotic microangiopathy and the human anti-pig cellular immune response remain as significant impediments to successful clinical xenotransplantation," scientists in Sydney, Australia report.

"NKG2D is an activating immunoreceptor found on human natural killer (HuNK) cells, CD8(+) and gamma delta T cells. Signaling through NKG2D mediates cytotoxicity and cytokine secretion by NK cells and co-stimulation of T cells. Chinese hamster ovary P...

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Source: Medical Devices and Surgical Technology Week (2009-01-11)

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