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Stem Cell Research

New stem cell research findings from Shanghai Jiao Tong University described

Published in Medical Devices and Surgical Technology Week, February 22nd, 2009

According to recent research published in the journal Transplantation Proceedings, "Although previous studies have demonstrated that stromal-derived factor-1 (SDF-1) played a key role in chronic graft dysfunction (CGD), the precise mechanisms underlying this process are not clear. In this study, SDF-1 was injected into keratinocyte stem cells (KSCs) which were isolated and purified from neonatal C57BL/6 (H-2b) mice."

"Adenylyl cyclase (AC) activity of KSCs was measured and expressions of the human major histocompatibility complex (MHC) class I chain-related antigens A and B (MICA, MICB) detected by immunofluorescence. Cultured KSCs were negative for WE MHC class...

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