DNA Research

Research data from University of Nebraska update understanding of DNA research

Published in Medical Devices and Surgical Technology Week, May 3rd, 2009

"This paper describes protocols for studies of structure and dynamics of DNA and protein-DNA complexes with atomic force microscopy (AFM) utilizing the surface chemistry approach. The necessary specifics for the preparation of functionalized surfaces and AFM probes with the use of silanes and silatranes, including the protocols for synthesis of silatranes are provided," scientists writing in the journal Methods report.

"The methodology of studies of local and global conformations DNA with the major focus on the time-lapse imaging of DNA in aqueous solutions is illustrated by the study of dynamics of Holliday junctions including branch migration. The analysis of...

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Source: Medical Devices and Surgical Technology Week (2009-05-03)

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