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Medical Devices & Surgical Technology Week

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Journal of the National Cancer Institute



Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer



July 5th, 2009

Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer Institute.

In the study, Manon van Engeland, Ph.D., of the Department of Pathology at Maastricht University Medical Center in the Netherlands, and colleagues examined N-Myc downstream-regulated gene 4 (NDRG4) as a novel tumor suppressor and biomarker.

The researchers analyzed NDRG4 promoter methylation and expression in human colorectal cancer cell lines, noncancerous colon mucosa, and colorectal cancer tissue....


Source: Medical Devices & Surgical Technology Week (2009-07-05)

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