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World Journal of Gastroenterology

Is 31P MRS a useful tool for evaluating early acute hepatic radiation injury?

Published in Medical Devices and Surgical Technology Week, July 12th, 2009

Acute hepatic radiation injury could lead to necrosis of hepatocytes, fatty degeneration and hepatic fibrosis. At the present, the gold standard test is liver biopsy. However, this procedure is invasive, uncomfortable for the patients and sometimes results in serious complications. 31P magnetic resonance spectroscopy (MRS) has been used to study liver metabolism in vivo for several years. A research team led by Jian-Shan Mao from Zhejiang University investigated whether changes of 31P MRS in the liver with early acute radiation injury were related to the liver damage score (LDS) and pathologic changes. They also determined the value of 31P MRS in detecting early acute hepatic radiation...

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