Malaria

Researchers from University of Amsterdam detail findings in malaria

Published in Medical Devices and Surgical Technology Week, March 21st, 2010

According to a study from Netherlands, "Severe falciparum malaria remains a major killer in tropical countries. Central in the pathophysiology is mechanical obstruction in the microcirculation caused by cytoadherence and sequestration of parasitized erythrocytes."

"However, the pathogenesis of many features complicating severe malaria, including coma, renal failure and thrombocytopenia, remains incompletely understood. These disease manifestations are also key features of thrombotic thrombocytopenic purpura, a life-threatening disease strongly associated with a deficiency of the von Willebrand factor (VWF) cleaving protease, ADAMTS13. We measured plasma ADAMTS13...

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Source: Medical Devices and Surgical Technology Week (2010-03-21)

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