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Crohn Disease

Investigators at Cleveland Clinic zero in on Crohn disease

Published in Medical Devices and Surgical Technology Week, April 18th, 2010

"Crohn's disease is generally considered a relative contraindication for restorative proctocolectomy with ileal pouch anastomosis (IPAA). The natural history of IPAA in these patients has not well been defined," scientists writing in the journal Alimentary Pharmacology & Therapeutics report.

"To evaluate the natural history of IPAA in patients with a well-defined preoperative Crohn's disease. All patients from the Pouchitis Clinic who had a preoperative diagnosis of Crohn's disease were screened and 11 patients met the inclusion criteria. The control group (with a 1:4 ratio) consisted of IPAA patients with a preoperative diagnosis of UC. During the follow-up...

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