Pathology
Data on Pathology Described by S. Calabuig-Farinas et al
Published in Medical Devices and Surgical Technology Week, October 2nd, 2011
2011 OCT 2 -- "Gastrointestinal stromal tumors (GISTs) are c-KIT-signaling-driven mesenchymal tumors of the human digestive tract, many of which have c-KIT or PDGFR alpha activating mutations. The authors studied the immunohistochemical markers, c-KIT and PDGFR alpha mutations, in GISTs and their association with the clinicopathological and clinical follow-up in 145 GISTs," scientists writing in the International Journal of Surgical Pathology report.
"Tumors were located mainly in the stomach, the median tumor size being 7.5 cm. The mitotic index was <= 5 mitoses per 50 high-power fields in 61% of cases, 96% expressed CD117, and c-KIT or PDGFR...
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