General Surgery

New General Surgery Study Findings Recently Were Published by Researchers at Mayo Clinic

Published in Medical Devices and Surgical Technology Week, February 19th, 2012

2012 FEB 19 -- According to the authors of recent research from Rochester, Minnesota, "GLUT2 is translocated to the apical membrane of enterocytes exposed to glucose concentrations >similar to 50 mM. Mechanisms of GLUT2-mediated glucose uptake in cell culture models of enterocytes have not been studied."

"To explore mechanism(s) of glucose uptake in 3 enterocyte-like cell lines. Glucose uptake was measured in Caco-2, RIE-1, and IEC-6 cell lines using varying concentrations of glucose (0.5-50 mM). Effects of phlorizin (SGLT1 inhibitor), phloretin (GLUT2 inhibitor), nocodazole and cylochalasin B (disrupters of cytoskeleton), calphostin C and chelerythrine...

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Source: Medical Devices and Surgical Technology Week (2012-02-19)

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