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Acadia Pharmaceuticals, Inc.

Favorable results presented from phase Ib/IIa trial of ACP-103

Published in Medical Imaging Business Week, July 29th, 2004

Acadia Pharmaceuticals, Inc., (ACAD) presented, at the CNS Diseases Congress held in Philadelphia, results of a phase Ib/IIa clinical trial of ACP-103 in patients with Parkinson disease and results from a human brain receptor occupancy study of ACP-103 performed using position emission tomography (PET).

Results of these studies demonstrated that ACP-103, Acadia's proprietary 5-HT2A inverse agonist, was safe and well tolerated in Parkinson disease patients at drug plasma levels many fold higher than those required for maximal brain occupancy of the 5-HT2A receptors, suggesting a large therapeutic index.

ACP-103 was discovered by scientists at Acadia...

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