University of Michigan
Microdialysis with capillary LC/MS3 used to monitor rat neuropeptide levels
Published in Medical Imaging Business Week, April 21st, 2005
In a recent study from the United States, "[i]n vivo microdialysis sampling was coupled to capillary liquid chromatography (LC)/electrospray ionization quadrupole ion trap mass spectrometry (MS) to monitor [Met]enkephalin and [Leu]enkephalin in the striatum of anesthetized and freely-moving rats."
"The LC system utilized a high-pressure pump to load 2.5 microL samples and desalt the 25 microm i.d. by 2 cm long column in 12 min," reported H.M. Baseski and coauthors at the University of Michigan. "Samples were eluted with a separate pump at approximately 100...
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