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University of Nantes, France

Studies from France, the United States and Japan advance knowledge in HIV/AIDS research

Published in Medical Imaging Business Week, July 20th, 2006

HIV/AIDS research advances have been reported from France, the United States and Japan.

Study 1: Polymorphism in the perforin gene is not conclusively associated with HIV disease progression.

"Cytotoxic T lymphocytes (CTLs) play an essential role in the control of viral replication during human immunodeficiency virus (HIV) infection. However, the efficacy of the CTL response varies between individuals," researchers in France report.

According to the authors, "We tested the hypothesis that genetic polymorphisms in the lytic effector molecule perforin could influence the progression of HIV infection. The perforin gene was screened...

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