Bone Substitutes

Researchers at University of Cologne target bone substitutes

Published in Medical Imaging Business Week, September 18th, 2008

"The objective of this study was to evaluate the role of collagen membrane and Bio-Oss(R) coverage in healing of an onlay graft to the mandible. Twelve adult sheep each received an onlay bone graft (experiment 1), bone graft + Bio-Gide(R) (experiment 2), and bone graft + Bio-Oss(R)/Bio-Gide(R) (experiment 3) on the lateral surface of the mandible," scientists in Cologne, Germany report.

"The animals were euthanized at 4, 8, 12 or 16 weeks after surgery, and findings were analysed by routine microscopy and immunohistochemistry for proliferation (Ki67) and apoptotic (Caspase-3) markets. Grafts were fully incorporated in all specimens. Pronounced resorption was observed in...

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Source: Medical Imaging Business Week (2008-09-18)

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