CSIC, Madrid
Raman spectroscopy-based assay may improve diagnosis
Published in Medical Imaging Law Weekly, August 31st, 2004
"At present, there are no efficient antemortern diagnostic tests for transmissible spongiform encephalopathys (TSEs), particularly in blood," scientists in Spain noted. "New strains of prion PrPSc, which causes TSEs, are currently appearing, and researchers remain concerned that if prion variants continue to emerge, some of them may escape detection by existing immunoassay tests."
"Because a common structural feature of PrPSc strains is their high content of beta sheets, Raman spectroscopy has proven to be a suitable technique to analyze a key membranous fraction...
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