MIT, Charlestown

Age-related changes in white matter microstructure characterized

Published in Medical Imaging Law Weekly, August 2nd, 2005

Age-related changes in white matter (WM) microstructure have been characterized using diffusion tensor imaging (DTI).

Cerebral WM "undergoes various degenerative changes with normal aging, including decreases in myelin density and alterations in myelin structure," neurologists in the United States explained.

In a recent study, D.H. Salat and coauthors at MIT "acquired whole-head, high-resolution diffusion tensor images" from "38 participants across the adult age span."

"Maps of fractional anisotropy (FA), a measure of WM microstructure, were calculated for each participant to determine whether particular fiber systems of the brain...

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Source: Medical Imaging Law Weekly (2005-08-02)

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