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Dartmouth College, U.S.

Findings from the United States and Denmark advance knowledge in hematology research

Published in Medical Imaging Law Weekly, September 12th, 2006

Reports from the United States and Denmark highlight recent research in hematology.

Study 1: In coronary artery disease patients, plasminogen complexed with tissue plasminogen activator (tPA) exists in a conformation that enables increased tPA activity and plasminogen conversion to plasmin.

Investigators writing in the Journal of Thrombosis and Haemostasis report, "While coronary artery disease (CAD) is associated with disturbances of the plasma fibrinolytic system, the nature of these disturbances is not fully defined. Fibrinolysis is regulated by plasmin, whose production is mediated by plasminogen activator conversion of plasminogen (Plg)...

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