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Synlab Center, Heidelberg, Germany

Angiotensin-I converting enzyme I/D variant is not linked to diabetes in coronary angiography

Published in Medical Imaging Law Weekly, October 31st, 2006

The angiotensin-I converting enzyme I/D polymorphism is not associated with type 2 diabetes in individuals undergoing coronary angiography.

"The deletion (D) allele of the angiotensin-I converting enzyme (ACE) is associated with higher ACE activity and has been implicated only recently in the pathogenesis of type 2 diabetes in Caucasian subjects. We have studied the ACE I/D polymorphism in 1054 patients with type 2 diabetes and in 2251 individuals without type 2 diabetes in Caucasians persons undergoing coronary angiography," investigators in Germany report.

T.B. Grammer and associates working with the Synlab Center explained, "Further parameters of...

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