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Non-Hodgkin Lymphoma

Study results from J. Coulot and colleagues update understanding of non-hodgkin lymphoma

Published in Medical Imaging Law Weekly, January 15th, 2008

According to recent research from Villejuif, France, "Radio immunotherapy with anti-CD20 antibodies (Abs) labeled with beta-emitters is now used in the treatment of non-Hodgkin's lymphoma (NHL). Because Y-90 is a pure beta-emitter, no direct image of its distribution can be obtained in humans."

"In this paper, we present in this study imaging data of Y-90-Ab distribution in human-mantle-cell lymphoma within a mouse model. Describing the actual distribution of the radionuclide at the level of particles range may have important impact on patient dosimetry and therapy treatment planning. NOD/SCID mice were grafted with a human NHL cell line that involves the bone marrow....

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