Tissue Engineering

Research on tissue engineering described by Y. Guan and colleagues

Published in Medical Imaging Law Weekly, March 25th, 2008

According to recent research from Tianjin, People's Republic of China, "Acquired or congenital abnormalities may lead to urethral damage or loss, often requiring surgical reconstruction. Urethrocutaneous fistula and strictures are common complications, due to inadequate blood supply."

"Thus, adequate blood supply is a key factor for successful urethral tissue reconstruction. In this study, urethral grafts were prepared by seeding rabbit bladder urothelial cells (UCs) modified with human vascular endothelial growth factor (VEGF(165)) gene in the decellularized artery matrix. A retroviral pMSCV-VEGF(165)-GFP vector was cloned by insertion of VEGF open reading frame into...

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Source: Medical Imaging Law Weekly (2008-03-25)

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